2021.12.07 12:02 autotldr New data shows GSK-Vir drug works against all Omicron mutations
This is the best tl;dr I could make, original reduced by 13%. (I'm a bot)
Dec 7 - British drugmaker GSK said on Tuesday its antibody-based COVID-19 therapy with U.S. partner Vir Biotechnology is effective against all mutations of the new Omicron coronavirus variant, citing new data from early-stage studies.
The data, yet to be published in a peer-reviewed medical journal, shows that the companies' treatment, sotrovimab, is effective against all 37 identified mutations to date in the spike protein, GSK said in a statement.
Last week, another pre-clinical data showed that the drug had worked against key mutations of the Omicron variant.
Sotrovimab is designed to latch on to the spike protein on the surface of the coronavirus, but Omicron has been found to have an unusually high number of mutations on that protein.
"These pre-clinical data demonstrate the potential for our monoclonal antibody to be effective against the latest variant, Omicron, plus all other variants of concern defined to date by the WHO," GSK Chief Scientific Officer Hal Barron said.
GSK and Vir have been engineering so-called pseudoviruses that feature major coronavirus mutations across all suspicious variants that have emerged so far, and have run lab tests on their vulnerability to sotrovimab treatment.
Post found in /Coronavirus, /news and /socialscience.
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2021.12.07 12:02 HockeyMod Game Thread: New York Rangers (16-4-3) at Chicago Blackhawks (9-13-2) - 07 Dec 2021 - 08:30PM EST
New York Rangers (16-4-3) at Chicago Blackhawks (9-13-2) United Center Comment with all tables
PT MT CT ET AT 05:30PM 06:30PM 07:30PM 08:30PM 09:30PM TV NBCSCH, MSG 2 Listen NYR - CHI Other-Away Preview - Boxscore - Recap Other-Home Preview - Boxscore - Recap GameCenter On NHL.com
2021.12.07 12:02 kez248 Elite 4... I think u mean earthquake simulator
2021.12.07 12:02 emqyww66 How is CRW 1301 beginning Poetry Writing? Anyone has experience in this class
2021.12.07 12:02 AmericanGirl1493 We agreed to keep things casual, now he's giving me mixed messages
I (28F) met a guy (33M) on a dating app in early September. We went on a few great dates together and I was having a lot of fun getting to know him. I'm in a place where I'm looking for something more serious and was excited to see where it was going. It became clear that we were most likely on different pages - I felt he wanted to rush into things sexually (no judgement), and it became hard to figure out time to go on dates which was frustrating because I'm really busy and last minute plans don't really work for me.
I ended up breaking things off with him but was polite about it and there wasn't any bad blood between us, just felt like it wasn't working out. After about a month or two of not speaking, he reached out to me and asked me to get drinks - I was hesitant at first but we started talking again and eventually meeting again in person.
Long story short, because of how he behaved before I really don't see this going somewhere serious with him, but he was fun to hook up with so I was open to keeping things casual. To give some more background, I'm not super sexually experienced and have been wanting to explore more so when he asked if we could keep things casual I agreed and figured it wouldn't hurt to have some fun while also pursuing dating other people more seriously.
Last week we made plans for me to come over one night after work and we ordered dinner and watched a movie. After a few drinks, he said something like "I can't figure out if you actually like me" and asked if we could be casual but still go out together sometimes. I asked him to elaborate on that and when he started stumbling over his words, I told him if we're going to keep this fun and casual he can't be confusing and give me mixed messages and moved on from the conversation.
We ended up having a fun night together but when I woke up I couldn't help but think about his weird commentary and slightly mixed messages. Any thoughts on how to handle?
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2021.12.07 12:02 Minimum_Razzmatazz35 Clover Finance CLV Price Prediction [CRAZY BUY OPPORTUNITY] Dec 07 2021
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2021.12.07 12:02 whoatemypie7 What do you guys think of Ankur Warikoo?
I just think he's a pretentious piece of f***, a spoilt brat from a privileged background, who just got lucky copying some foreign business model and now goes around giving gyaan like he knows life inside out.
I watched his morning routine video and gosh the pretentiousness was annoying as f. "F you" was my immediate thought.
And all the gyaan he keeps giving about investment, how one should follow one's "passion", sab chhodke abhi startup karo etc etc etc. Abbe chutiye, tere jaise hi logon ke karan aaj ka youth itna gumrah hai bc.
And his motherf***ing pretentiousness, madarchod. So damn annoying.
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2021.12.07 12:02 master_3425 who doesn't like eevee
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2021.12.07 12:02 ExitAbove Traveling to India for work. Any chance on finding a YM 40 on Oysterflex in an AD?
2021.12.07 12:02 quarter-circle-punch 0/2 2/4 11/4 7/3 1/3 10/4 1/2 2/2 2/3 0/1 1/2 4/3 1/1 0/4 0/2 0/3 6/3 7/3 7/3 4/3 2/4 7/3 2/3 11/4 7/3 1/3
2021.12.07 12:02 HeroXinfinite Platinum Quests!
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2021.12.07 12:02 Ad73738282 Por que homem pensa que mulher bonita é legal?
Uma colega de trabalho veio me dizer que tinha um cara querendo me conhecer porque tinha me achado muito bonita, e dai caralhoo??? De onde vocês tiram que mulher bonita quer papo? E dai se eu sou bonita? Nunca viu mulher bonita não? Vão atrás das feias que são legais, eu sou um porre lá vou perder meu tempo conversando com necessitado!!
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2021.12.07 12:02 Wutbot1 Wutbot on "Loss, Tax": [r/wallstreetbets] Harvest for a tax loss or hang on?
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2021.12.07 12:02 MisterSalami ich🎶iel
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2021.12.07 12:02 onlytoesausbabe Just me living out my dreams, being Santa's little helper
2021.12.07 12:02 QuantumThinkology Alibaba’s DAMO Academy Successfully Develops World’s First 3D Stacked In-Memory Computing Chip Based on DRAM. Alibaba Cloud claims this is a breakthrough that can help overcome the von Neumann bottleneck, a limitation on throughput caused by the standard personal computer architecture
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2021.12.07 12:02 YoungQuahogMoney Kids don't always come first.
2021.12.07 12:02 sammitye What’s your death row meal?
2021.12.07 12:02 introsort [Hiring] QA (Fleet) - Fleet - Careers (JetBrains)
2021.12.07 12:02 GleithCZ Do you think there is more 9/10 blondes than 9/10 brunettes, but less 10/10 blondes than 10/10 brunettes?
2021.12.07 12:02 lss_bvt_and_16 Hello World
2021.12.07 12:02 Ghostryder33 Apple dongle vs laptop sound quality with headphones
I have this laptop OMEN by HP 17-cb0002ng and a brand new legion 5 pro ( 5800h 3070 ) and I have a problem with the sound quality of the latter one., not to mention the volume, which is so powerful
I have 2 main pairs of headphones that I use : Sony MDR-1A and MDR -1AM2 plus some other cheap stuff
On my Omen the sound is so rich and vibrant without any eq or thinkering but on my lenovo legion 5 pro the sound is not just way lower in volume, but the quality, oh my is just trash in comparison. So i had this apple type c dongle and I tried it and improved the quality on lenovo substntialy in both loudness and sound quality. But still compared with the HP's raw 3.5mm jack sound is not that ''rich'' is definetly enjoyble but not the same.
( Could the fact that is written '' bang&olufsen'' on my laptop have anything to do with all this. even tough there is no 3rd party app installed ? )
I don't understand why on hp the sound quality is so much better with that realtek onboard stuff. The lows and mids are better compared with that dongle which I find strange. Could someone explain me how this stuff works ? And If anyone knows a dongle / amp something portable in the range of 50-100 euro to use with lenovo to recommend as I have no knoweledge with this stuff. I would be tempted to refuse that lenovo just for the sake of sound quality.
Weren't laptop's onboard sound supposed to be average at best, like is the case with this legion 5 pro ?
I tried with equalizerapo / Peace to eq the dongle with no succes to sound quality, just the increase in volume. I found also some eq profiles here https://github.com/jaakkopasanen/AutoEq/tree/masteresults but no succes also.
From what I saw on audio science review this dongle should've been an improvment compared with onboard audio, which it is in the case of lenovo, but not at the level of this hp...
Is there any way to find what type of sound profile/eq or kind off sound curve (I don't know how to call it) one source, in this case my HP has ?
Or the only way is to buy something ?
Sorry for beeing probably annoying :) and for eventuals misspells.
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2021.12.07 12:02 Flaky-Syrup7265 How do you feel, when you buy something for 0.002ETH and sell it for 1.2ETH? The pixelboi punks holders will be awarded free accounts in "META" Now the floor price is 0.02 ETH and it will go high soon! Link in Comments
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2021.12.07 12:02 xpertarts One Stroke Acrylic Painting 😍 Hope you like it 😍
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2021.12.07 12:02 TrueLaLand86 Silencio. Parte 3
Si bien el camino era algo largo, la ruta era mitad empedrado y mitad asfalto; decorada por la selva a sus costados y lleno de cerros a su alrededor; una verdadera belleza impactante. Para llegar, había que hacer dos escalas: primero bajar en la Ruta, después de la entrada del pueblo, y la otra en la rotonda del pueblo, que se llegaba a pie; allí tenían que esperar a los tíos que venían con la camioneta F-100 adaptada para los caminos de la zona y luego los llevarían hasta la estancia de la familia Betanzos, la estancia de la familia de Laurita.
Pero algo sacudió la tranquilidad de los pescadores de Nemesio Parma
-chamigo...un pacú, un surubí, un dorado… o un chupabarro o una tararira ni que fuera...no pica nada che...
-vos dijiste… eso porque sos feo y le asustas bromeaban los pescadores.
Los encandiló una luz cerca de un tacuaral.