2021.10.16 19:38 IamRobort [H] Red Eye Glass Mini Recycler [W] $30 PayPal
2021.10.16 19:38 Antisanghiantimullah Where North Korean defectors are deported to
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2021.10.16 19:38 hayirtesekkurler BU NE YAKIŞIKLILIK ELHAMDÜLILLAH SUBHANALLAH
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2021.10.16 19:38 Desperate-Entry2417 but it'll be the one week the reddit will be 10/10
2021.10.16 19:38 BatDudeCole20 Me when
2021.10.16 19:38 major_wood_num2 I assume this is not accurate.
3/2 for $850?
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2021.10.16 19:38 Emoriiisp I need someone to buy me a new bra
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2021.10.16 19:38 justanotherswetalian Is this a normal fade or is there something wrong? Yellow and crispy leaves
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2021.10.16 19:38 SK_121 Best way to invest and make coins. Already build a team for now. Just want to know the best way to make more coins and invest I have around 135k
2021.10.16 19:38 acmed Cicala - Red Rocks [alt country/emo country] (2021)
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2021.10.16 19:38 mypeeweehurts the new mobs
2021.10.16 19:38 Efficient-Sir-2539 I'm the guitarist for a rock/grunge band called Mothertown. 4 weeks ago we released our song "In the Room". It would be great if you could give a listen to it and tell me what you think. Thanks a lot :)
2021.10.16 19:38 bambibunkins Made a DIY cardboard house for my bunnies. I had my eye on a $70 one on Etsy but this works just the same. Besides bunnies don’t care about aesthetics ;)
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2021.10.16 19:38 zhiurovas Can someone refute this statement implying that r/genzedong is an unreliable source?
Not Russian, and I can’t speak for modern Russia, but I have studied up some on Soviet history and wouldn’t exactly trust genzedong as a reliable source of information when it comes to the Soviet Union. When dealing with history, you always need to keep in mind any biases that may be present, and in the case of genzedong, they’re typically young westerners who lean far-left and have a positive bias towards Soviet history, which may impact the information they share, whether it be true or false. While I’m a left-leaning westerner myself, I also have a bit of experience with history, and it’s always important to look for biases when it comes to intaking any information regarding the subject. In this case, there are two things you have to keep in mind-
2021.10.16 19:38 Pronobis4 Memino
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2021.10.16 19:38 zsmithworks Missouri man given to 16 life sentences for child sex abuse - Midland Daily News
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2021.10.16 19:38 ProposalHairy7350 please can you guys tell me if this is a type of magic mushroom? uk
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2021.10.16 19:38 sadgrimesfan Cute lil fall forest ✨
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2021.10.16 19:38 baloozabash_games is it better to rescale before or after?
ok, so I want to ask whether or not it's better to record in 1440x900 and use the rescale output in obs or to record in 1440x900 and edit like that then rescale the final video which is better?
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2021.10.16 19:38 Kinggingr Free tickets - for Parent + Child
It’s not easy or cheap to be a parent. I have 2 open seats in section 124 and i want these to go to the right place, so anyone looking to take their kid, nephew, or neighbor, just go have a blast on me.
Feel free to use the money saved on ice cream after the game, cold stone is only walking distance away :)
FYI you’ll need vaccine or negative test results to be able to enter the Banc.
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2021.10.16 19:38 FelixFelicis17b If you’re awake say hi :)🥰
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2021.10.16 19:38 Intrepid_Jacket_3321 What is your opinion on lizzo's outfit at Carbi Bs Birthday?
2021.10.16 19:38 NotFrankCastle “Juice Loosener” for Day 9 of #inkhomer
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2021.10.16 19:38 fairlycommonplace Here’s the “After” picture from my last post in higher quality, still a cute girl one year later
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2021.10.16 19:38 ImpulsiveBehaviors [M/27] No psychoactive drugs have any effect after abusing phenibut. Psychiatrists cannot treat me as no drugs work. What kind of doctor should I see?
Age: 27 Sex: Male Medications: Gabapentin 600MG daily Height: 6’1 Weight: 160 LB’s
TLDR at bottom.
Hello great people of Reddit.
Here’s my problem: Psychiatrists cannot treat me with psychoactive drugs as almost all drugs do not work anymore, and the cause is because I took phenibut for 3 years (GABA-B agonist, VGCC modulator) - And while taking it, as well as after quitting phenibut, no psychoactive drugs have any effect whatsoever. - I quit phenibut a year ago.
The only drugs that still work are Gabaergics/benzos to some extent. I currently take Gabapentin 600MG daily that was prescribed for phenibut withdrawal. It is also a calcium channel blocker like phenibut, but it doesn’t effect the GABA-B receptor which is the cause of my issue.
All other drugs do not work, this includes drugs of abuse, and psychoactive medications. The problem is no doctors have any clue why, and have no clue what I’m talking about.
I will explain why this has occurred further below.
But here’s my question: What kind of doctor would be the best in understanding neurochemistry in regards to drug-effected neuro receptors, and treating the problem, or helping me understand better?
It would take too long to “fully” explain here, but I will elaborate. I also posted in drugs regarding this if you want to read more.
From my multi-year long, extremely in-depth research, the GABA-B receptor is responsible for the neurotransmission and effects of psychoactive chemicals. Stimulating AS WELL as down-regulation of the receptor causes my problem, but such little research has been done in this regard that every doctor I’ve spoken to has absolutely no clue what I’m talking about.
Here’s a study that elaborates and explains how GABA-B agonists can cause this, and here’s a quote that from the article that touches on it.
“Metabotropic GABA(B) receptors are widely distributed throughout the brain. Alterations in GABA signaling through pharmacological activation or deactivation of the GABA(B) receptor regulate behavior and brain reward processes. GABA(B) receptor agonists and, most recently, positive modulators have been found to inhibit the reinforcing effects of drugs of abuse, such as cocaine, amphetamine, nicotine, ethanol, and opiates.”
Here’s another study that was conducted with rats and GABA-B, the rats did not respond to methamphetamine while also taking a GABA-B agonist.
Scroll down to the second image that shows brain activity for specific reference.
In addition: Doctors are under the preliminary belief that the GABA-B receptor may play the most significant role in depression. It is also critically important for the balance of all other neurotransmitters. Stimulating the gaba-B receptor will provide you with a strong sense of well being, euphoria, energy, motivation, confidence, feeling calm, better sleep, among so many other subtle effects.
psychiatrists cannot treat my mental issues (Depression using wellbutrin for example, or any other psychoactive medication)
TL;DR: Took phenibut for 3 years. While using it, and after quitting no other psychoactive drugs / medication work whatsoever, and from my research this is due to the GABA-B receptor which is responsible for receptor transmission from agonists. Need to know what kind of doctor to see.
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